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Second, a long lapse : if weeks pass without a dose, the tolerability that was built up erodes, and the documented conservative approach is to re-initiate lower rather than resume at the last dose reached

Abiotic controls were also carried out in parallel in a separate reactor, to monitor for any contamination during the experiment

refer to current batch COA Testing methods: HPLC with UV detection coupled with Mass Spectrometry Fill Weight Confirmation: Net content verification for lot consistency Batch verification: Batch-specific COA available when applicable COA & Batch Verification Each applicable batch is documented with available analytical records to support product identification and quality review

Handling: Let cold or frozen vials warm to room temperature before opening so condensation wont form, and keep the solution clear of heat and direct light